Warnings and
We, the Editors and Publisher of the journal Bioengineered, have retracted the following article:
When the FDA
The effect of mirtazapine on QTc interval was assessed in a clinical randomized trial with placebo and positive (moxifloxacin) controls involving 54 healthy volunteers using exposure response analysis
2 A number of drugs have been implicated in prolongation of the QT interval, including
For calculating the QTc interval, most commonly Bazett's square root formula (QTc = QT/RR 0
2 A number of drugs have been implicated in prolongation of the QT interval, including
Many commonly used
Mirtazapine is generally well tolerated in medically ill patients with and without formal psychiatric comorbidity to target sleep, appetite, nausea, and pain
Risk factors for QT prolongation include female gender, increasing age, family history, hypokalaemia and interactions with other medicines (Table 1)
The risk of drug-induced prolongation of QT is much higher in older adults and people with multiple
Linear e-max modelling suggested that prolongation of QTc intervals remained below the threshold for clinically meaningful The effect of REMERON (mirtazapine) on QTc interval was assessed in a clinical randomized trial with placebo and positive (moxifloxacin) controls involving 54 healthy volunteers using exposure response analysis
2
This trial showed a positive relationship between mirtazapine concentrations and prolongation of the QTc interval
His initial laboratory investigation revealed acute renal failure, low serum albumin, high serum potassium and
Mirtazapine (MTZ) is an antidepressant drug with an exceptional pharmacological profile
The effect of REMERON (mirtazapine) on QTc interval was assessed in a clinical randomized trial with placebo and positive (moxifloxacin) controls involving 54 healthy volunteers using exposure response analysis
Design A cross sectional study using electrocardiographic, prescribing, and clinical data from electronic health records to